Company Filing History:
Years Active: 2019
Title: Étienne Gagnon: Innovator in Protein Complex Monitoring
Introduction
Étienne Gagnon is a notable inventor based in Montreal, Canada. He has made significant contributions to the field of biochemistry through his innovative patent related to protein complex formation monitoring. His work is essential for advancing our understanding of cellular processes.
Latest Patents
Gagnon's patent, titled "Systems and methods for the monitoring of protein complex formation in cells," describes a bioluminescence resonance energy transfer (BRET) based system. This system allows for real-time monitoring of ternary complex formation in live cells with high sensitivity and accuracy. The technology enables energy transfer between a luciferase donor and intermediate and terminal acceptors, minimizing contaminating signals. Additionally, the system can be adapted for quaternary complex detection by incorporating a protein complementation assay (PCA) component. This innovation is broadly applicable to detecting various protein complexes, including those involving nuclear receptors, GPCRs, Receptor Tyrosine Kinase (RTKs), multimeric enzymes, or structural proteins.
Career Highlights
Étienne Gagnon is affiliated with the Université de Montréal, where he conducts his research and development. His work has garnered attention for its potential applications in understanding complex biological interactions.
Collaborations
Gagnon has collaborated with notable colleagues, including David Cotnoir-White and Sylvie Mader. These partnerships have contributed to the advancement of his research and the development of innovative solutions in the field.
Conclusion
Étienne Gagnon's contributions to the monitoring of protein complex formation represent a significant advancement in biochemistry. His innovative patent and collaborative efforts continue to influence research in this vital area.