Ángel De Jesús Corria Osorio

Title: The Innovative Mind of Ángel De Jesús Corria Osorio

Introduction

Ángel De Jesús Corria Osorio, an accomplished inventor based in Granma, CU, has made significant contributions to the field of biotechnology. With a focused expertise in polypeptides and their applications, his innovative work has the potential to impact various medical fields, particularly in immunomodulation.

Latest Patents

Ángel holds a patent for "TGFβ-derived polypeptides and uses thereof". This invention relates to mutated polypeptides of the TGFβ molecule, designed to possess a high homology with the sequence of human TGFβ. These muteins strategically lose their ability to interact with ALK5 while retaining functionality with other receptors within the receptor complex, specifically TβRII and TβRIII. The significant property of these polypeptides is their ability to antagonize the signaling of natural variants of TGFβ ligands, which is dependent on ALK5 recruitment in the receptor complex. This innovative approach has notable immunomodulatory effects and could be pivotal in treating diseases such as cancer, conditions related to fibrosis, and chronic infectious diseases.

Career Highlights

Ángel is actively affiliated with the Centro de Inmunología Molecular, where he applies his expertise in biotechnology to develop pioneering solutions for health challenges. His career is marked by his commitment to research and development in the field, leading to impactful innovations like his patented polypeptides.

Collaborations

Throughout his career, Ángel has collaborated with esteemed colleagues such as Kalet León Monzón and Tania Carmenate Portilla. These collaborations have fostered a rich environment for innovation and progress, enabling the development of biotechnology applications that can enhance medical treatments.

Conclusion

Ángel De Jesús Corria Osorio's work exemplifies how targeted innovations in biotechnology can lead to groundbreaking advancements in healthcare. With a strong patent portfolio and collaborations with talented professionals, he continues to strive toward improving the immune response in various medical conditions, showcasing the power of invention in transforming lives.