Ziwei Huang

Title: Innovations by Inventor Ziwei Huang

Introduction

Ziwei Huang is a notable inventor based in Champaign, IL (US). He has made significant contributions to the field of immunology, particularly in developing methods to inhibit undesired immune responses. With a total of 10 patents, his work has the potential to impact treatments for various diseases.

Latest Patents

Huang's latest patents focus on mimetics of CD4 that inhibit immune response. The application details a method for identifying compounds that block the interaction of CD4 and MHC, class II, gene products. This method can be used to treat diseases such as multiple sclerosis and to prevent graft rejection and graft versus host disease. The compounds he has developed mimic specific portions of the human CD4 lymphocyte cell surface antigen, with molecular weights ranging from about 1400 to 400. Specific examples include cyclic peptides and peptidomimetics.

Another significant patent involves CD4-derived peptides that also inhibit immune responses. Similar to his previous work, this application outlines a method for identifying compounds that can block the interaction of CD4 and MHC, class II, gene products. The potential applications for these compounds are the same, targeting diseases like multiple sclerosis and preventing graft-related complications.

Career Highlights

Throughout his career, Huang has worked with esteemed institutions, including Thomas Jefferson University. His research has been pivotal in advancing our understanding of immune responses and developing therapeutic strategies.

Collaborations

Huang has collaborated with notable individuals in his field, including Robert Korngold and Jialun Wang. These partnerships have contributed to the success of his research and innovations.

Conclusion

Ziwei Huang's contributions to immunology through his patents and research are noteworthy. His work has the potential to lead to significant advancements in treating immune-related diseases.