Zhengtao Li

Title: Innovations of Zhengtao Li

Introduction

Zhengtao Li is a prominent inventor based in Pudong New District, China. He has made significant contributions to the field of nucleic acid research, holding a total of 3 patents. His work focuses on the development of methods for site-specific enzymatic labeling of nucleic acids, which has important implications in biotechnology and molecular biology.

Latest Patents

One of Zhengtao Li's latest patents is titled "Method for the site-specific enzymatic labelling of nucleic acids in vitro by incorporation of unnatural nucleotides." This patent describes analogs of unnatural nucleotides that feature predominantly hydrophobic nucleobase analogs. These analogs are capable of forming unnatural base pairs during DNA polymerase-mediated replication or RNA polymerase-mediated transcription. The introduction of these unnatural nucleobases into oligonucleotides allows for site-specific cleavage or the provision of a reactive linker that can undergo functionalization with cargo-bearing reagents.

Career Highlights

Throughout his career, Zhengtao Li has worked with esteemed institutions such as The Scripps Research Institute and the U.S. Government's National Institutes of Health Division of Extramural Inventions and Technology Resources. His innovative research has contributed to advancements in the understanding and manipulation of nucleic acids.

Collaborations

Zhengtao Li has collaborated with notable scientists in his field, including Floyd E. Romesberg and Denis A. Malyshev. These collaborations have further enhanced the impact of his research and innovations.

Conclusion

Zhengtao Li's work in the field of nucleic acids exemplifies the importance of innovation in scientific research. His patents and collaborations highlight his contributions to advancing biotechnology and molecular biology.