Company Filing History:
Years Active: 2002
Title: Innovations by Zhaoda Zhang in Oligonucleotide Synthesis
Introduction
Zhaoda Zhang is an accomplished inventor based in Shrewsbury, MA, known for his significant contributions to the field of oligonucleotide synthesis. With a total of two patents to his name, Zhang has developed innovative chemical processes that enhance the efficiency and effectiveness of oligonucleotide production.
Latest Patents
Zhaoda Zhang's latest patents include "Sulfur transfer reagents for oligonucleotide synthesis" and "Preparation of nucleoside phosphoramidites and oligonucleotide synthesis." The first patent focuses on the chemical synthesis of oligonucleotides, specifically the sulfurization of internucleoside linkages. This invention introduces new sulfur transfer reagents that are not only inexpensive to produce but also stable in storage and highly efficient in their application. The second patent presents novel bifunctional phosphitylating reagents that facilitate the in situ preparation of 5′-protected nucleoside phosphoramidites. These reagents react quickly under neutral or weakly basic conditions, eliminating the need for additional activation steps and allowing for the chemoselective generation of nucleoside phosphoramidites without prior purification.
Career Highlights
Zhaoda Zhang is currently employed at Avecia Biotechnology, Inc., where he continues to advance his research in biotechnology and chemical synthesis. His work has significantly impacted the field, providing researchers with more efficient tools for oligonucleotide synthesis.
Collaborations
Zhaoda Zhang collaborates with Jin-Yan Tang, a fellow researcher, to further explore innovative solutions in their field. Their partnership exemplifies the collaborative spirit that drives advancements in biotechnology.
Conclusion
Zhaoda Zhang's contributions to oligonucleotide synthesis through his innovative patents demonstrate his expertise and commitment to advancing chemical processes. His work at Avecia Biotechnology, Inc. continues to influence the field positively.