Company Filing History:
Years Active: 2019-2023
Title: Zehra Dincer: Innovator in Stem Cell Research
Introduction
Zehra Dincer is a prominent inventor based in New York, NY (US). She has made significant contributions to the field of stem cell research, particularly in the specification of cranial placode derivatives. With a total of 2 patents, her work is paving the way for advancements in sensory and endocrine organ development.
Latest Patents
One of her latest patents focuses on the specification of functional cranial placode derivatives from human pluripotent stem cells. Cranial placodes are essential embryonic structures that play a crucial role in the development of sensory and endocrine organs. This patent discloses an efficient method for deriving cranial placodes from human pluripotent stem cells. The process involves the timed removal of the BMP inhibitor Noggin, which is part of the dual-SMAD inhibition strategy for neural induction. This removal triggers placode induction while minimizing central nervous system fates. Further fate specification at the pre-placode stage allows for the selective generation of placode-derived trigeminal ganglia, mature lens fibers, and anterior pituitary hormone-producing cells. These cells, upon transplantation, can produce hormones such as human growth hormone and adrenocorticotropic hormone in vivo. Additionally, anterior pituitary hormone-producing cells can also be generated in vitro.
Career Highlights
Zehra Dincer is affiliated with the Memorial Sloan Kettering Cancer Center, where she continues her groundbreaking research. Her work has garnered attention for its potential applications in regenerative medicine and therapeutic interventions.
Collaborations
Some of her notable coworkers include Stuart Chambers and Lorenz Studer, who contribute to her research endeavors.
Conclusion
Zehra Dincer is a trailblazer in the field of stem cell research, with her innovative patents and contributions significantly impacting the development of sensory and endocrine organs. Her work exemplifies the potential of human pluripotent stem cells in medical advancements.