South Bend, IN, United States of America

Zdenek Slouka

USPTO Granted Patents = 5 

 

Average Co-Inventor Count = 4.3

ph-index = 1

Forward Citations = 3(Granted Patents)


Location History:

  • Prague, CI (2020)
  • South Bend, IN (US) (2019 - 2022)

Company Filing History:


Years Active: 2019-2022

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5 patents (USPTO):Explore Patents

Title: Innovations by Zdenek Slouka

Introduction

Zdenek Slouka is a prominent inventor based in South Bend, Indiana. He has made significant contributions to the field of microfluidics and molecular detection. With a total of 5 patents, his work has advanced the capabilities of diagnostic technologies.

Latest Patents

One of his latest patents is titled "AC electrosprayed droplets for digital and emulsion PCR." This invention provides an alternating current electrospray technology that can generate micron-sized droplets in oil at very high throughput for emulsion or digital PCR (Polymerase Chain Reaction). This technology outperforms the throughput of the current gold standard in droplet generation using flow-focusing technology by at least a factor of 100. The design is simple and can generate a billion to a trillion monodispersed droplets in about one hour. This is much faster than flow-focusing, which is limited to a few million droplets per hour. The droplet size and generation rate can also be easily adjusted by changing the voltage of the AC electric field. The range of produced droplet sizes is about 1-100 microns, wherein the droplets are monodispersed in size.

Another significant patent is the "Integrated membrane sensor for rapid molecular detection." This patent discloses methods, compositions, and devices for an integrated, heterogeneous ion-exchange membrane-based plastic microfluidic biochip platform that can be used to detect multiple diagnostic markers present in real samples. Its various components can be easily integrated in a modular fashion for different applications. Automated control allows sequential and dynamic activation of different components on the chip. The integrated platform consists of three units and is designed to execute the following functions: (i) separation of the target biomolecules from the real sample, (ii) localizing and concentrating the targeted molecules at a specific location in the microfluidic chip, and (iii) detection of the targeted molecules using hybridization/docking events against a complementary ssDNA oligoprobe sequence or a specific antibody.

Career Highlights

Zdenek Slouka is affiliated with the University of Notre Dame Du Lac, where he continues to innovate and contribute to research in his field. His work has garnered attention for its practical applications in diagnostics and molecular biology.

Collaborations

He has collaborated with notable colleagues such as Satyajyoti Senapati

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