Location History:
- Amherst, NY (US) (1976)
- Buffalo, NY (US) (1980 - 1982)
Company Filing History:
Years Active: 1976-1982
Title: Yung-Chi Cheng: Innovator in Nucleoside Chemistry
Introduction
Yung-Chi Cheng is a prominent inventor based in Buffalo, NY (US). He has made significant contributions to the field of nucleoside chemistry, particularly in the development of novel compounds with potential therapeutic applications. With a total of 3 patents, Cheng's work focuses on creating nucleosides and nucleotides that exhibit antitumor, antiviral, and antimicrobial properties.
Latest Patents
Cheng's latest patents include innovative processes for preparing 2-azido-2-deoxyarabinofuranosyl halides. These compounds are crucial for synthesizing novel arabinofuranosyl nucleosides and nucleotides. The processes involve the condensation of a pyrimidine, purine, or 1,3-oxazine base with an acylated 2-azido-2-deoxyarabinofuranosyl halide. Following this, deblocking and catalytic hydrogenation are performed to convert the 2'-azido group to a 2'-amino group. Additionally, alkylation can be applied to transform the 2'-amino group into a 2'-hydrocarbylamino group.
Career Highlights
Cheng's career is marked by his dedication to advancing the field of medicinal chemistry. His innovative approaches have led to the development of compounds that hold promise for treating various diseases. His work is recognized for its potential impact on healthcare and pharmaceutical research.
Collaborations
Cheng has collaborated with notable colleagues, including Miroslav V Bobek and Alexander Bloch. These partnerships have fostered a collaborative environment that enhances the research and development of new therapeutic agents.
Conclusion
Yung-Chi Cheng's contributions to nucleoside chemistry exemplify the importance of innovation in the pharmaceutical industry. His patents reflect a commitment to developing compounds that could significantly improve treatment options for patients.