Yun Zhang

Title: The Innovations of Yun Zhang

Introduction

Yun Zhang is a prominent inventor based in Hangzhou, China. He has made significant contributions to the field of biochemistry, particularly in the development of enzyme mutants. His work focuses on enhancing the catalytic efficiency of enzymes, which has important implications for various applications.

Latest Patents

Yun Zhang holds a patent for a cocaine esterase mutant and its use. The patent discloses a cocaine esterase mutant obtained by mutating a wildtype cocaine esterase. The amino acid sequence of the wildtype cocaine esterase is shown as SEQ ID No. 1. The cocaine esterase mutant is characterized by the mutations T172R/G173Q/L196C/I301C, with the possibility of additional mutations such as V116K or A51 site mutations. The A51 site mutation can be L, Y, V, F, or W. This mutant demonstrates greatly improved catalytic efficiency on the cocaine toxic metabolite benzoylecgonine compared to the wildtype enzyme.

Career Highlights

Yun Zhang is affiliated with Hangzhou Normal University, where he conducts research and develops innovative solutions in his field. His work has garnered attention for its potential to address issues related to cocaine metabolism and toxicity.

Collaborations

Yun Zhang collaborates with notable colleagues, including Xiabin Chen and Jianzhuang Yao. Their combined expertise contributes to the advancement of research in enzyme technology and its applications.

Conclusion

Yun Zhang's contributions to the field of biochemistry, particularly through his patented cocaine esterase mutant, highlight his innovative approach to enzyme research. His work not only enhances our understanding of enzyme efficiency but also opens new avenues for therapeutic applications.