Yuh-Meei Lin

Title: Yuh-Meei Lin: Innovator in Antiviral and Antimycobacterial Compounds

Introduction

Yuh-Meei Lin is a prominent inventor based in Naperville, Illinois, known for her significant contributions to the field of medicinal chemistry. With a total of six patents to her name, she has focused her research on developing compounds that target various infectious diseases, particularly those caused by mycobacterium and viral agents.

Latest Patents

Among her latest patents, Lin has developed beta-fluoroethyl thiourea compounds aimed at preventing or treating mycobacterial infections. These compounds include naturally occurring and synthetic biflavonoids, flavonoids, chalcones, and chalcone-like compounds. The research demonstrated that eight of these compounds exhibited over 90% inhibition of Mycobacterium tuberculosis growth at a concentration of 12.5 µg/mL. The minimum inhibitory concentrations (MIC) for the preferred compounds ranged from 6.8 to 48.3 µM. Additionally, she has worked on antiviral biflavanoids, including robustaflavone and its derivatives, which have shown effectiveness against various viral infections such as hepatitis B and HIV-1.

Career Highlights

Lin has held positions at notable companies, including Advanced Life Sciences, Inc. and Medichem Research, Inc. Her work has been instrumental in advancing the understanding and treatment of infectious diseases through innovative chemical compounds.

Collaborations

Throughout her career, Lin has collaborated with esteemed colleagues, including Michael T. Flavin and David E. Zembower, contributing to a rich exchange of ideas and research findings in her field.

Conclusion

Yuh-Meei Lin's innovative work in developing antiviral and antimycobacterial compounds has made a significant impact in the field of medicinal chemistry. Her contributions continue to pave the way for new treatments for infectious diseases.