Company Filing History:
Years Active: 2022-2025
Title: Yuguang Wang: Innovator in Soluble Guanylate Cyclase Stimulation
Introduction
Yuguang Wang is a prominent inventor based in Cambridge, MA, known for his significant contributions to the field of pharmaceutical chemistry. He has been instrumental in developing novel processes for the preparation of soluble guanylate cyclase stimulators, which have important therapeutic applications.
Latest Patents
Yuguang Wang holds four patents, with his latest focusing on processes and intermediates for the preparation of soluble guanylate cyclase stimulators. The present disclosure relates to novel processes for the preparation of compounds of Formula I. Some of these compounds are useful as stimulators of soluble guanylate cyclase (sGC). Others serve as useful intermediates towards the preparation of said stimulators. These processes are amenable to large-scale preparation and produce stable 3-(2-pyrimidinyl) pyrazoles of Formula I in high purity and yields. The present invention has the additional advantage of facile reaction conditions, which are amenable to scale-up for large-scale manufacturing. The disclosure also provides novel intermediates useful in the preparation of these compounds.
Career Highlights
Yuguang Wang is currently associated with Cyclerion Therapeutics, Inc., where he continues to advance his research and development efforts. His work has significantly impacted the pharmaceutical industry, particularly in the area of cardiovascular therapies.
Collaborations
Yuguang Wang collaborates with notable colleagues, including Debra Jane Wallace and Fenger Zhou, who contribute to his innovative projects and research initiatives.
Conclusion
Yuguang Wang's work in the development of soluble guanylate cyclase stimulators showcases his expertise and dedication to advancing pharmaceutical science. His contributions are paving the way for new therapeutic options in the treatment of various health conditions.