Company Filing History:
Years Active: 1995-1998
Title: Innovations of Yoshihiko Umegae
Introduction
Yoshihiko Umegae is a notable inventor based in Yokohama, Japan. He has made significant contributions to the field of enzymatic assays, holding a total of 3 patents. His work focuses on enhancing the accuracy and sensitivity of measurements in various biochemical applications.
Latest Patents
One of Yoshihiko Umegae's latest patents is a method of assay of enzymatic activity and the apparatus for performing it. This method involves projecting excitation light onto a sample that contains an enzyme, a substrate that forms a product through the enzyme's action, and a reference substance that is insensitive to the enzyme but emits fluorescence. The process includes obtaining a first measured value of fluorescence intensity at a specific wavelength region, which includes fluorescence emitted by the substrate or the product. Additionally, a second measured value of fluorescence intensity is obtained at a different wavelength region that includes fluorescence emitted by the reference substance. The enzymatic activity is then assayed from the ratio of these two measured values. This innovative method assures high accuracy and high sensitivity in enzyme-labeled immunoassays and enzyme-labeled DNA hybridization.
Career Highlights
Yoshihiko Umegae is currently associated with Tosoh Corporation, where he continues to develop and refine his innovative methods. His work has been instrumental in advancing the field of enzymatic assays, making significant impacts in both research and practical applications.
Collaborations
Yoshihiko has collaborated with notable coworkers, including Hidechika Hayashi and Yukio Mitsuhisa. Their combined expertise has contributed to the successful development of his patented methods.
Conclusion
Yoshihiko Umegae's contributions to enzymatic assay technology highlight his innovative spirit and dedication to scientific advancement. His patents reflect a commitment to improving measurement accuracy and sensitivity in biochemical applications.