Yosef Shiloh

Title: Yosef Shiloh: Innovator in Genetic Research

Introduction

Yosef Shiloh is a prominent inventor based in Tel Aviv, Israel. He has made significant contributions to the field of genetics, particularly in understanding ataxia-telangiectasia. With a total of 7 patents, his work has had a profound impact on genetic research and medical science.

Latest Patents

Among his latest patents is the discovery of the ataxia-telangiectasia gene and its genomic organization. This includes a purified and isolated gene, designated ATM, whose mutations are known to cause ataxia-telangiectasia. His work also encompasses methods for detecting the defective gene, the purified polypeptide encoded by this gene, and antibodies that recognize the defective protein. Additionally, he has provided a purified amino acid sequence selected from the group of Sequence ID No.: 3 and its analogs, which are crucial for understanding the mutations that lead to ataxia-telangiectasia.

Career Highlights

Yosef Shiloh has worked with notable institutions, including Ramot University Authority for Applied Research and Industrial Development Limited. His research has been pivotal in advancing the understanding of genetic disorders and their implications for human health.

Collaborations

Some of his notable coworkers include Danilo A Tagle and Francis S Collins, who have also made significant contributions to the field of genetics.

Conclusion

Yosef Shiloh's innovative work in genetic research has led to important discoveries that enhance our understanding of ataxia-telangiectasia. His contributions continue to influence the field and pave the way for future advancements in genetic science.