Yongsheng Wang

Title: Innovations of Yongsheng Wang in Genetic Engineering

Introduction

Yongsheng Wang is a prominent inventor based in Sichuan, China. He has made significant contributions to the field of genetic engineering, particularly in the development of advanced therapeutic techniques for cancer treatment. His innovative work focuses on enhancing the immune response against tumors.

Latest Patents

Yongsheng Wang holds a patent for a "Genetically engineered dual-targeting chimeric antigen receptor and use thereof." This invention addresses the up-regulated expression of PD-L1 in tumor cells and immune cells exposed to malignant serosal cavity effusion. The dual-targeting chimeric antigen receptor he developed is designed to competitively bind to PD-L1, transforming an inhibition signal into an activation signal. This mechanism enhances the killing activity of T cells, while the introduction of 4-1BB promotes T cell proliferation and survival. The invention also includes a host cell expressing this dual-targeting antigen receptor, which can be utilized in preventing or treating solid tumors.

Career Highlights

Yongsheng Wang is affiliated with Sichuan University, where he conducts his research and development activities. His work has garnered attention for its potential impact on cancer therapies, showcasing his commitment to advancing medical science through innovative solutions.

Collaborations

Yongsheng Wang collaborates with notable colleagues, including Qizhi Ma and Dan Li. Their combined expertise contributes to the advancement of research in genetic engineering and cancer treatment.

Conclusion

Yongsheng Wang's contributions to genetic engineering, particularly through his patented innovations, highlight the potential for new cancer therapies. His work exemplifies the intersection of science and technology in addressing critical health challenges.