Beijing, China

Yongbo Liu

USPTO Granted Patents = 1 

Average Co-Inventor Count = 6.0

ph-index = 1


Company Filing History:


Years Active: 2025

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1 patent (USPTO):

Title: Innovations by Yongbo Liu: A Breakthrough in Medicinal Chemistry

Introduction

Yongbo Liu is a prominent inventor based in Beijing, China. He has made significant strides in the field of medicinal chemistry, specifically through his patented work on nitrogen-containing polycyclic fused ring compounds. His contributions are vital for the development of pharmaceutical compositions that hold promise for targeted cancer therapy.

Latest Patents

Yongbo Liu holds one patent titled "Nitrogen-containing polycyclic fused ring compound, pharmaceutical composition thereof, preparation method therefor and use thereof." This innovative compound is notable for its selective and effective inhibition of the RET oncogene. It displays a robust inhibitory effect on several clinically relevant RET mutants, including the gatekeeper residue mutant RET V804M and the solvent-front residue mutant RET G810R. Additionally, it has shown effectiveness against RET wild-type and the growth inhibition of the TT cell line derived from thyroid cancer, as well as Ba/F3 cells transformed by various RET mutants. The compound has the potential not only to halt cell proliferation but also to induce cell death in TT cells.

Career Highlights

Yongbo Liu is currently associated with Applied Pharmaceutical Science, Inc., where he has utilized his extensive expertise in synthetic chemistry to develop innovative pharmaceutical solutions. His work has contributed significantly to the advancement of targeted cancer treatments.

Collaborations

Throughout his career, Yongbo Liu has collaborated with several talented professionals, notably Jun Zhong and Libin Liu. These collaborations have been instrumental in driving forward the research and development of new pharmacological compounds.

Conclusion

Yongbo Liu's contributions to medicinal chemistry exemplify the intersection of innovation and practical application in pharmaceuticals. His groundbreaking patent on nitrogen-containing polycyclic fused ring compounds underscores the importance of targeted therapies in cancer treatment, highlighting a promising path for future medical advancements.

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