Yinghe Hu

Title: Yinghe Hu: Innovator in G-Protein Coupled Receptor Research

Introduction

Yinghe Hu is a prominent inventor based in San Diego, CA, known for his significant contributions to the field of biochemistry and molecular biology. With a focus on G-protein coupled receptors (GPCRs) and phosphodiesterase isoforms, he has developed innovative solutions that have the potential to advance medical diagnostics and treatments.

Latest Patents

Yinghe Hu holds 2 patents that showcase his expertise and innovative spirit. His latest patents include:

1. **Universal G-protein coupled receptor reporter constructs** - This invention provides universal GPCR reporter constructs that comprise a serum response element, a cAMP response element, and a multiple response element. These constructs are capable of detecting activities of all GPCRs examined. Additionally, the invention includes host cells harboring a universal GPCR reporter construct, as well as assays for detecting modulators of GPCRs using these host cells.

2. **Cyclic AMP phosphodiesterase isoforms and methods of use** - This patent discloses human and rat cAMP phosphodiesterase isoforms, denoted PDE4Ds, along with the DNA (RNA) encoding such polypeptides. The methods outlined in this patent are designed for diagnostic assays to identify mutations in nucleic acid sequences encoding these polypeptides. Furthermore, it details how to detect altered levels of the polypeptide as a means of diagnosing diseases and screening potential modulators, particularly inhibitors, of the novel PDE4Ds.

Career Highlights

Throughout his career, Yinghe Hu has worked with notable companies, including Memory Pharmaceuticals Corporation and Irm LLC. His work has significantly impacted the understanding and application of GPCRs in therapeutic contexts.

Collaborations

Yinghe Hu has collaborated with esteemed colleagues, including Xiaonan Xin and Axel Unterbeck, contributing to a rich exchange of ideas and advancements in their field.

Conclusion

Yinghe Hu's innovative work in the realm of GPCRs and phosphodiesterase isoforms exemplifies the potential of scientific research to lead to groundbreaking medical advancements. His patents reflect a commitment to improving diagnostic and therapeutic strategies in healthcare.