Company Filing History:
Years Active: 2022
Title: Yanbo Wen: Innovator in Vaccine Development
Introduction
Yanbo Wen is a prominent inventor based in Beijing, China. He has made significant contributions to the field of vaccine development, particularly in relation to the Marburg virus. His innovative work has the potential to impact public health positively.
Latest Patents
Yanbo Wen holds a patent for a recombinant human replication-deficient adenovirus that comprises a modified nucleic acid encoding the Marburg virus envelope glycoprotein. This invention relates to a nucleotide sequence for encoding a Marburg virus envelope glycoprotein and a human replication-deficient recombinant adenovirus capable of expressing this nucleotide sequence. The application of this invention is particularly relevant in the preparation of a vaccine against Marburg virus disease. The vaccine utilizes an E1 and E3 deleted replication-deficient human type-5 adenovirus as a vector, along with HEK293 cells integrating an adenovirus E1 gene as a packaging cell line. The protective antigen gene carried is a codon-optimized Marburg virus Angola strain envelope glycoprotein gene, which shows significant expression in transfected cells after codon optimization.
Career Highlights
Yanbo Wen is affiliated with the Academy of Military Medical Science, where he conducts his research and development work. His career is marked by a commitment to advancing medical science and improving vaccine technologies.
Collaborations
He has collaborated with notable colleagues, including Wei Chen and Shipo Wu, to further enhance his research efforts and contribute to the scientific community.
Conclusion
Yanbo Wen's innovative work in vaccine development showcases his dedication to addressing critical health challenges. His contributions, particularly in relation to the Marburg virus, highlight the importance of scientific research in improving public health outcomes.