Yan-Ling Zhang

Title: Yan-Ling Zhang: Innovator in Bordetella Pertussis Toxin Production

Introduction

Yan-Ling Zhang is a notable inventor based in Rockville, MD (US). He has made significant contributions to the field of microbiology, particularly in the production of Bordetella pertussis toxin. His work has implications for vaccine development and public health.

Latest Patents

Yan-Ling Zhang holds a patent for the "Production of Bordetella pertussis toxin with a low concentration of iron." This patent describes a fermentation-level cultivation of Bordetella pertussis bacteria on a commercial scale. The critical factors in large-scale cultivation include the presence of an antifoam agent and the maintenance of proper oxygen levels and iron content in the culture medium. The pertussis toxin produced by the bacteria parallels the rate of growth of the bacteria, highlighting the importance of these cultivation conditions.

Career Highlights

Yan-Ling Zhang is associated with the United States of America as represented by the Department of Health. His work has been instrumental in advancing the understanding of Bordetella pertussis and its toxin production. His research contributes to the broader field of infectious diseases and vaccine development.

Collaborations

Yan-Ling Zhang has collaborated with notable colleagues such as Ronald D Sekura and Joseph Shiloach. These collaborations have likely enhanced the research and development efforts in his field.

Conclusion

In summary, Yan-Ling Zhang is a prominent inventor whose work in Bordetella pertussis toxin production has significant implications for public health. His contributions continue to influence the field of microbiology and vaccine research.