Xini Zhang

Title: Innovations by Inventor Xini Zhang in Rocuronium Development

Introduction

Xini Zhang, an accomplished inventor based in Zhejiang, China, has made significant contributions to the pharmaceutical industry with a focus on the preparation and purification of rocuronium. With two patents to his name, Zhang's innovative methods highlight the advancements in muscle relaxants used during anesthesia.

Latest Patents

One of Xini Zhang's latest patents is a revolutionary preparation method for rocuronium. The invention utilizes 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstan-3α-ol-17β-acetate as a starting material, which is directly reacted with 3-bromopropene at ambient temperature to yield rocuronium. This method emphasizes efficiency and safety in the synthesis process.

Additionally, Zhang holds a patent for a method for purifying rocuronium bromide. This process involves formulating crude rocuronium bromide into an aqueous solution, distilling off excess solvent at reduced pressure, and utilizing active carbon or silica gel for absorption. The solution is then filtrated, quick-frozen, and lyophilized to produce pure rocuronium bromide, ensuring a high-quality product for clinical use.

Career Highlights

Xini Zhang is currently employed by Zhejiang Huahai Pharmaceutical Co., Ltd., where he continues to contribute to pharmaceutical innovations. His expertise in organic chemistry and pharmaceutical manufacturing underlines his impactful role within the company. His advancements regarding rocuronium enhance the efficiency and effectiveness of surgical procedures where muscle relaxants are essential.

Collaborations

Throughout his career, Zhang has collaborated with notable coworkers, including Zhiwen Zeng and Peng Wang. These partnerships reflect the collaborative spirit of research and innovation in the pharmaceutical industry, enabling the sharing of knowledge and expertise to further enhance drug development processes.

Conclusion

Inventor Xini Zhang has emerged as a key figure in the pharmaceutical sector, particularly with his recent patents on rocuronium. Through his innovative approaches and collaborations, he is poised to make lasting contributions that could improve anesthesia practices and patient outcomes in surgical settings. Zhang's work not only showcases individual brilliance but also reflects the importance of collaboration in advancing medical technology.