Company Filing History:
Years Active: 2014
Title: Innovations in Cardiac Tissue Engineering by Xin Jiang
Introduction
Xin Jiang is an accomplished inventor based in Chestnut Hill, MA (US). He has made significant contributions to the field of cardiac tissue engineering. His work focuses on the generation of vascularized human heart tissue, which has important implications for treating cardiovascular disorders.
Latest Patents
Xin Jiang holds a patent titled "Generation of vascularized human heart tissue and uses thereof." This invention relates to the generation of vascularized human heart tissue from human primordial Islet1-positive (ISL1+) progenitors. The patent outlines methods for isolating human ISL1+ primordial cells from human pluripotent cells, such as human embryonic stem cells. These primordial cells can differentiate into various lineages, including cardiomyocyte, endothelial, and smooth muscle lineages. The invention also discusses the therapeutic use of these progenitors for treating cardiovascular disorders and congenital heart disease.
Career Highlights
Xin Jiang is associated with The General Hospital Corporation, where he continues to advance research in cardiac tissue engineering. His innovative approaches aim to create in vivo humanized models of vascular disease, which can be used to assess drug toxicity and identify agents that influence coronary blood flow.
Collaborations
Xin Jiang has collaborated with notable colleagues, including Kenneth R. Chien and Lei Bu. These partnerships have further enhanced the research and development of his groundbreaking work in the field.
Conclusion
Xin Jiang's contributions to the generation of vascularized human heart tissue represent a significant advancement in medical science. His innovative approaches hold promise for improving treatments for cardiovascular diseases.