Company Filing History:
Years Active: 2020
Title: Innovations of Wolfgang H Schmied in Unnatural Amino Acid Incorporation
Introduction
Wolfgang H Schmied is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of biotechnology, particularly in the incorporation of unnatural amino acids into proteins. His innovative methods have the potential to advance various applications in protein engineering and synthetic biology.
Latest Patents
Wolfgang H Schmied holds a patent titled "Use of eRF1 mutants in unnatural amino acid incorporation." This invention relates to a method for incorporating an unnatural amino acid into a protein of interest within a eukaryotic cell. The method involves several steps, including providing a eukaryotic cell that expresses an orthogonal tRNA synthetase-tRNA pair, a nucleic acid sequence encoding the protein of interest, and a mutant eRF1. The mutant eRF1 has an amino acid sequence with at least 60% sequence identity to the human wild type eRF1 sequence. The process allows for the incorporation of an unnatural amino acid into the protein via the orthogonal tRNA synthetase-tRNA pair.
Career Highlights
Wolfgang H Schmied is associated with United Kingdom Research and Innovation, where he continues to explore the frontiers of protein synthesis. His work has garnered attention for its potential applications in therapeutic development and biotechnological advancements. With a focus on enhancing the capabilities of protein engineering, Schmied's contributions are paving the way for future innovations in the field.
Collaborations
Wolfgang has collaborated with esteemed colleagues such as Jason W Chin and Simon J Elsasser. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and expertise, further enhancing the impact of their research.
Conclusion
Wolfgang H Schmied's innovative work in the incorporation of unnatural amino acids into proteins represents a significant advancement in biotechnology. His contributions are likely to influence future research and applications in the field, showcasing the importance of innovation in scientific discovery.