William P Kolb

Title: The Innovations of William P. Kolb

Introduction

William P. Kolb is a notable inventor based in Del Mar, California. He has made significant contributions to the field of biomedical research, particularly in the area of complement activation and blood sample processing. With a total of 2 patents, Kolb's work has implications for clinical diagnostics and therapeutic applications.

Latest Patents

Kolb's latest patents include a method for the prevention of spontaneous complement activation in mammalian biological samples. This invention utilizes selected polyhydroxyl compounds, including monosaccharides, disaccharides, and oligosaccharides, to effectively prevent complement activation in vitro. The presence of an anticoagulant and a divalent cation chelator enhances this effect. This innovation allows for the storage of clinical samples at conventional temperatures ranging from -20°C to +22°C for extended periods before performing complement protein assays. Additionally, Kolb has developed a method to remove red blood cells from whole blood samples using various acids. This process results in an essentially RBC-free serum or plasma sample, which is crucial for accurate laboratory analysis.

Career Highlights

William P. Kolb is currently associated with Quidel Corporation, where he continues to advance his research and innovations. His work has been instrumental in improving the reliability of clinical tests and enhancing the quality of biological samples used in diagnostics.

Collaborations

Kolb has collaborated with notable colleagues, including Theodore T. Sand and Barbara McLaughlin, contributing to a dynamic research environment that fosters innovation and development in biomedical sciences.

Conclusion

William P. Kolb's contributions to the field of biomedical research through his patents and collaborations highlight his role as a significant inventor. His work not only advances scientific knowledge but also has practical applications that benefit clinical diagnostics.