Wei-Jen Tang

Title: Wei-Jen Tang: Innovator in Adenylyl Cyclase Research

Introduction

Wei-Jen Tang is an accomplished inventor based in Chicago, IL, known for his groundbreaking work in the field of biochemistry, particularly focusing on adenylyl cyclase and its implications in bacterial pathogenesis. With two patents to his name, he has made significant contributions that are relevant to both basic science and potential therapeutic applications.

Latest Patents

Wei-Jen Tang's latest patents include innovative methods and compositions relating to anthrax pathogenesis. One notable patent details the structures of Edema Factor alone and its complex with calmodulin, as determined through x-ray crystallography. This work has led to the development of a method for assaying potential inhibitors of bacterial infection, involving a systematic approach with calmodulin-activated adenylyl cyclase exotoxin. His other patent focuses on a soluble form of adenylyl cyclase, presenting methods for screening stimulators and inhibitors of adenylyl cyclase activity. This inventive chimera combines features of type I and type II adenylyl cyclases while lacking transmembrane domains, ensuring solubility while maintaining functional activity.

Career Highlights

Throughout his career, Wei-Jen Tang has been associated with prestigious institutions such as the University of Texas System and the University of Chicago. His involvement in academic and research settings has allowed him to advance his expertise in biochemistry and patentable inventions, leading to impactful research that enhances our understanding of biological mechanisms.

Collaborations

Wei-Jen Tang has collaborated with prominent scientists, including Alfred G. Gilman and Andrew Bohm, enriching his research with diverse insights and fostering innovative approaches to scientific problems. These collaborations have not only propelled his studies but have also contributed to the broader scientific community.

Conclusion

In summary, Wei-Jen Tang's contributions as an inventor reflect his commitment to advancing the field of biochemistry. With his patents focused on adenylyl cyclase and bacterial pathogenesis, he continues to pave the way for future innovations and potential therapeutic advancements. His work is a testament to the intersection of scientific inquiry and practical application that drives innovation in the life sciences.