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Years Active: 2011
Title: Walter Gehring: Innovator in Cellular Manipulation
Introduction
Walter Gehring is a prominent inventor based in Therwil, Switzerland. He has made significant contributions to the field of cellular biology, particularly in the manipulation of tissue and organ types through innovative methods. His work focuses on the Notch signaling pathway, which plays a crucial role in cell fate determination.
Latest Patents
Walter Gehring holds a patent for his invention titled "Manipulation of tissue of organ type using the notch pathway." This invention is directed to methods for altering the fate of a cell, tissue, or organ type by modifying Notch pathway function. The invention also encompasses methods for changing the activation state of the Notch pathway alongside one or more cell fate control gene pathways. This technology can be applied to cells of any differentiation state, allowing for the expansion of resulting cells for use in cell replacement therapy. Such advancements can aid in the regeneration of diseased or injured tissues. Additionally, the invention includes methods for treating macular degeneration by altering Notch pathway function in retinal pigment epithelium cells or retinal neuroepithelium. The patent also provides kits for generating cells, tissues, or organs with altered fates and methods for screening for Notch pathway agonists or antagonists.
Career Highlights
Walter Gehring has had a distinguished career, contributing to significant advancements in cellular biology. He has worked at esteemed institutions such as the University of Basel and Yale University, where he has collaborated with other leading scientists in the field.
Collaborations
One of his notable collaborators is Spyridon Artavanis-Tsakonas, with whom he has worked on various research projects related to cell signaling and fate determination.
Conclusion
Walter Gehring's innovative work in manipulating cellular pathways has the potential to revolutionize treatments for various diseases and injuries. His contributions to the field of cellular biology continue to inspire future research and development.