W K Wong

Title: The Innovative Contributions of W K Wong in Biotechnology

Introduction

W K Wong, an accomplished inventor based in Mississauga, Canada, has made significant contributions to the field of biotechnology through his innovative work on recombinant DNA constructs. With a total of two patents to his name, Wong's inventions have opened new avenues in the efficient excretion of heterologous proteins from E. coli.

Latest Patents

W K Wong's latest patent focuses on the development of a recombinant DNA construct that facilitates the excretion of heterologous proteins from E. coli. This construct comprises a coding region that aligns DNA coding for the heterologous protein with DNA coding for the OmpA signal peptide, enhancing the secretion of the protein into the periplasm. Additionally, the control region linked operably with the coding region features the tac promoter, the lac operator, and a consensus ribosome binding site. This innovative approach allows for the consistent excretion of a wide variety of heterologous proteins without needing carrier proteins or membrane-lytic agents, utilizing healthy E. coli hosts rather than mutant strains with defective outer membranes.

Career Highlights

Throughout his career, Wong has worked with notable companies in the biotechnology sector, including Allelix, Inc. and Astra AB. His expertise and innovative thinking have allowed him to contribute significantly to projects aimed at advancing protein engineering and biotechnology applications.

Collaborations

W K Wong has collaborated with Margaret L Sutherland, a fellow inventor, enhancing the collaborative efforts in their mutual fields of interest. Together, they have pushed the boundaries of what is possible in biotechnology, focusing on the efficient production of proteins.

Conclusion

W K Wong's innovative approaches and solutions to complex biotechnological challenges exemplify the impact that dedicated inventors can have in their fields. His patents not only demonstrate technical excellence but also highlight a commitment to advancing biotechnological applications that benefit various industries. As he continues to pioneer in the field, Wong's work remains a vital contribution to the world of scientific innovation.