Location History:
- Indianapolis, IN (US) (1987)
- Carmel, IN (US) (1989)
Company Filing History:
Years Active: 1987-1989
Title: Virginia A Birmingham: Innovator in Tylosin Resistance
Introduction
Virginia A Birmingham is a notable inventor based in Carmel, IN (US). She has made significant contributions to the field of biotechnology, particularly in the development of tylosin resistance-conferring genes. With a total of 3 patents, her work has implications for the construction of cloning vectors used in various organisms.
Latest Patents
Virginia's latest patents include the following innovations:
1. **Tylosin resistance-conferring gene, designated tlrC, for use in** - The tlrC gene is a novel tylosin resistance-conferring gene isolated from Streptomyces fradiae. It is utilized to construct several cloning vectors for use in Streptomyces. One such cloning vector, plasmid pSKC10, can be obtained in S. fradiae JS87 under the accession number NRRL 18072. S. fradiae JS87 is the preferred host when the tlrC gene is used to select tylosin-resistant Streptomyces transformants.
2. **Tylosin resistance-conferring gene, designated tlrB, for use in** - The tlrB gene is another novel tylosin resistance-conferring gene isolated from Streptomyces fradiae. It is also used to construct various cloning vectors for use in Streptomyces and related organisms. One such cloning vector, plasmid pSVB9, can be obtained in S. lividans under the accession number NRRL 18073. S. lividans is the preferred host when the tlrB gene is used to select tylosin-resistant Streptomyces transformants.
Career Highlights
Virginia A Birmingham is currently employed at Eli Lilly and Company, where she continues to advance her research in biotechnology. Her work has been instrumental in developing innovative solutions that enhance the understanding of antibiotic resistance in microbial organisms.
Collaborations
Virginia has collaborated with notable colleagues, including Eugene T Seno and Karen L Cox. These partnerships have fostered a collaborative environment that promotes innovation and research excellence.
Conclusion
Virginia A Birmingham's contributions to the field of biotechnology, particularly in the area of tylosin resistance, highlight her role as a leading inventor. Her patents and ongoing work at Eli Lilly and Company continue to impact the scientific community positively.