Tuchen Guan

Title: Tuchen Guan: Innovator in Silk Fibroin Nerve Grafts

Introduction

Tuchen Guan is a notable inventor based in Jiangsu, China. He has made significant contributions to the field of biomedical engineering, particularly in the development of nerve grafts. His innovative work focuses on utilizing silk fibroin for nerve regeneration, which has the potential to greatly enhance recovery from nerve injuries.

Latest Patents

Tuchen Guan holds a patent for a "Preparation method for silk fibroin nerve graft fused with NT3." This patent describes a method that synthesizes a gene fragment containing a silk fibroin light chain and NT-3. The process involves connecting the fragment to a pET-30 expression vector and transferring the recombinant expression vector into BL21 to obtain a fusion protein. The method further includes placing a silk fibroin fiber web in a mold, mixing the fusion protein with a silk fibroin solution, and performing freeze drying. This results in a silk fibroin nerve graft that provides mechanical support, nerve protection, and promotes nerve regeneration over time.

Career Highlights

Tuchen Guan is affiliated with Nantong University, where he continues to advance his research in the field of nerve regeneration. His work has garnered attention for its innovative approach to addressing nerve injuries, making significant strides in the biomedical field.

Collaborations

Tuchen has collaborated with colleagues such as Yan Liu and Mei Liu, contributing to a dynamic research environment that fosters innovation and development in their shared field of study.

Conclusion

Tuchen Guan's contributions to the development of silk fibroin nerve grafts represent a significant advancement in biomedical engineering. His innovative methods and collaborative efforts continue to pave the way for future research and applications in nerve regeneration.