Location History:
- Durham, NC (US) (1997)
- St. Louis, MO (US) (1996 - 1998)
Company Filing History:
Years Active: 1996-1998
Title: Todd Levine: Innovator in mRNA Research
Introduction
Todd Levine is a distinguished inventor based in St. Louis, MO (US), known for his significant contributions to the field of molecular biology. He holds three patents that focus on methods and compositions related to messenger RNA (mRNA) and its role in cellular growth and differentiation. His innovative work has implications for understanding and treating various cellular processes.
Latest Patents
Levine's latest patents include methods and compositions useful in the recognition and binding of mRNAs encoding functionally related proteins. These methods allow for the partitioning of mRNAs based on their binding to target sequences in the untranslated portions of the RNAs. His work describes the preparation of mRNA-subset libraries containing genes encoding growth regulatory factors, which are unique to specific cells, tissues, or tumors. This innovative approach provides a method for fingerprinting such factors. Another notable patent involves a peptide, Hel-N1, which binds to a 3'-untranslated mRNA sequence that is present in the messenger RNAs encoding oncoproteins and lymphokines. Hel-N1 mediates the specific destruction of these messenger RNAs, suppressing cell growth and promoting cellular differentiation.
Career Highlights
Throughout his career, Todd Levine has made significant strides in the field of mRNA research. His work has been instrumental in advancing our understanding of cellular growth and neoplasia. He has developed novel methods that enhance the study of growth regulatory factors, contributing to the broader field of molecular biology.
Collaborations
Levine has collaborated with notable researchers, including Jack D. Keene and FenBiao Gao. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Todd Levine's innovative work in mRNA research has led to significant advancements in understanding cellular processes. His patents reflect a commitment to exploring the complexities of gene expression and its implications for health and disease.