Company Filing History:
2 out of 73 
1 out of 1 
1 out of 1 Years Active: 2014-2020
Title: Tihamer Orban: Innovator in Autoimmune Disease Treatment
Introduction
Tihamer Orban is a notable inventor based in Brookline, MA (US), recognized for his contributions to the field of autoimmune disease treatment. With a total of 4 patents, Orban has made significant strides in developing innovative methods to address complex health issues.
Latest Patents
Orban's latest patents include groundbreaking methods for treating autoimmune diseases by inducing autoantigen-specific regulatory CD4+ T cells. These methods and compositions aim to treat and monitor the progress of autoimmune diseases, particularly focusing on diabetes mellitus. The techniques involve stimulating regulatory T cells that are specific to autoantigens associated with the disease. One specific embodiment relates to the prevention or delay of loss of residual β-cell mass, which can provide a longer remission period and delay the onset of diabetes-related complications through immunotherapeutic induction of regulatory T cells specific for human insulin B chain. Additionally, he has developed CTLA4 fusion proteins for the treatment of diabetes, which provide a method for treating, preventing, or delaying the progression of Type 1 diabetes mellitus autoimmunity by administering an effective amount of a CTLA4 molecule.
Career Highlights
Throughout his career, Tihamer Orban has worked with esteemed organizations such as the Joslin Diabetes Center, Inc. and Orban Biotech LLC. His work has significantly impacted the understanding and treatment of autoimmune diseases, particularly in relation to diabetes.
Collaborations
Orban has collaborated with various professionals in his field, including Peter Blackburn, to further advance his research and innovations.
Conclusion
Tihamer Orban's contributions to the field of autoimmune disease treatment through his innovative patents and collaborations highlight his dedication to improving health outcomes for individuals affected by these conditions. His work continues to pave the way for future advancements in medical science.