Location History:
- Medford, MA (US) (1987)
- Wakefield, RI (US) (1994 - 2006)
Company Filing History:
1 out of 2,962 
1 out of 3,446 
1 out of 40 
Years Active: 1987-2006
Title: Thomas N Mather: Innovator in Lyme Disease Research
Introduction
Thomas N Mather is a notable inventor based in Wakefield, RI (US). He has made significant contributions to the field of Lyme disease research, holding a total of 4 patents. His work focuses on understanding the interactions between ticks and the pathogens they transmit, which has important implications for public health.
Latest Patents
Mather's latest patents include the discovery of Ixodes salivary anticomplement protein, known as Isac. This novel protein exhibits anticomplement activity and can be isolated from the salivary glands of ticks or produced through recombinant DNA methods. Another significant patent involves the identification of tick saliva-induced Lyme disease spirochete antigens as vaccine candidates. This invention outlines a method for discovering new antigens from vector-borne pathogens by incubating viable pathogens in the saliva of their vector hosts. Three specific antigens, with molecular weights of approximately 19, 22, and 24 kDa, have been identified, providing a pathway for developing immunodiagnostics for Lyme disease and related disorders.
Career Highlights
Throughout his career, Thomas N Mather has worked with prestigious institutions, including Harvard College. His research has been pivotal in advancing the understanding of Lyme disease and its transmission through ticks. His innovative approaches have led to the development of potential diagnostic and therapeutic strategies.
Collaborations
Mather has collaborated with notable colleagues such as Jose-Marcos C Ribeiro and Andrew Spielman. These partnerships have enriched his research and contributed to the advancement of knowledge in the field of vector-borne diseases.
Conclusion
Thomas N Mather's contributions to Lyme disease research through his patents and collaborations highlight his role as an influential inventor in the field. His work continues to pave the way for advancements in diagnostics and treatment options for Lyme disease.