Baltimore, MD, United States of America

Thomas F Huff


Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 3(Granted Patents)


Company Filing History:


Years Active: 1988

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1 patent (USPTO):Explore Patents

Title: The Innovator Behind IgE Binding Factor: Thomas F. Huff

Introduction

Thomas F. Huff, an inventive mind hailing from Baltimore, MD (US), has made significant contributions in the field of molecular biology. With a focus on polypeptides exhibiting IgE binding factor activity, he holds a patent that reflects his innovative approach and research expertise.

Latest Patents

Huff's notable patent includes the development of CDNA clones coding for polypeptides exhibiting IgE binding factor activity. This patent features plasmid vectors that carry complementary DNA (cDNA) clones, where one particular clone possesses an open reading frame of 556 codons. The cDNA is derived from messenger RNA isolated from a rat/mouse T-cell hybridoma line, demonstrating his advanced knowledge in genetic research. The plasmid vector utilized in this patent also incorporates DNA segments from the SV40 virus, allowing for the expression of the cDNA to form a polypeptide with IgE potentiating activity after being transfected into a mammalian host cell, such as monkey Cos7 cells.

Career Highlights

Throughout his career, Thomas F. Huff has been affiliated with reputable institutions, including DNAX Research Institute of Molecular and Cellular Biology, Inc. and The Johns Hopkins University. His role in these organizations has allowed him to pioneer research initiatives that contribute to advancements in molecular biology and immunology.

Collaborations

During his journey, Huff has collaborated with notable colleagues such as Christine L. Martens and Kevin W. Moore. These collaborations reflect his commitment to collective scientific endeavor aimed at further enhancing the understanding of immunological responses and molecular mechanisms.

Conclusion

Thomas F. Huff continues to stand out as an influential inventor within the scientific community, particularly in the realm of molecular biology. His patent on CDNA clones showcases not only his inventive spirit but also the potential applications of his research in understanding IgE binding factors. As innovation progresses, the work of inventors like Huff plays a crucial role in driving scientific discovery and technology forward.

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