Virum, Denmark

Thomas Børglum Kjeldsen


Average Co-Inventor Count = 3.3

ph-index = 3

Forward Citations = 97(Granted Patents)


Company Filing History:


Years Active: 2001-2004

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3 patents (USPTO):Explore Patents

Title: Thomas Børglum Kjeldsen: Innovator in Insulin Production

Introduction

Thomas Børglum Kjeldsen is a notable inventor based in Virum, Denmark. He has made significant contributions to the field of biotechnology, particularly in the production of insulin and its precursors. With a total of 3 patents, his work has advanced the methods used in insulin production, benefiting both research and medical applications.

Latest Patents

Kjeldsen's latest patents include a method for making insulin precursors and insulin precursor analogues that have improved fermentation yield in yeast. This innovative approach provides novel insulin precursors and insulin precursor analogs that comprise a connecting peptide, known as mini C-peptide, which is preferably up to 15 amino acid residues long and includes at least one Gly. These precursors can be converted into human insulin or a human insulin analog, with specific structural requirements that enhance their functionality. Another significant patent involves N-terminally extended proteins expressed in yeast. This invention relates to polypeptides that are expressed and processed in yeast, along with a DNA construct that encodes such polypeptides, vectors carrying these DNA fragments, and yeast cells transformed with the vectors. This process facilitates the production of heterologous proteins in yeast, showcasing Kjeldsen's innovative approach to biotechnology.

Career Highlights

Kjeldsen is currently associated with Novo Nordisk A/S, a leading global healthcare company specializing in diabetes care and other chronic conditions. His work at Novo Nordisk has allowed him to contribute to groundbreaking advancements in insulin production and biotechnology.

Collaborations

Throughout his career, Kjeldsen has collaborated with esteemed colleagues such as Svend Havelund and Per Balschmidt. These collaborations have further enriched his research and development efforts in the field of insulin production.

Conclusion

Thomas Børglum Kjeldsen is a prominent figure in the field of biotechnology, particularly known for his innovative work in insulin production. His patents and contributions continue to influence the industry and improve healthcare outcomes.

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