Teresa L Born

Title: Teresa L Born: Innovator in Diagnostic Assays

Introduction

Teresa L Born is a prominent inventor based in Los Angeles, CA. She has made significant contributions to the field of molecular diagnostics, particularly in the detection of Neisseria gonorrhoeae. With a total of 3 patents, her work has advanced the capabilities of in vitro diagnostic assays.

Latest Patents

One of her notable patents is focused on hexapeptides of Neisseria gonorrhoeae. This patent discloses a nucleotide sequence characteristic of Neisseria gonorrhoeae, which serves as a basis for hybridization-type, nucleic acid-based, rapid diagnostic assays. The unique nature of this sequence allows for clear discrimination of N. gonorrhoeae from other Neisseria species, significantly reducing false positive readings. A 350 base pair N. gonorrhoeae DNA restriction fragment was cloned after subtractive hybridization to Neisseria meningitidis DNA. Further cloning experiments determined the sequences adjacent to the original fragment, demonstrating the ability to detect 105 of 106 N. gonorrhoeae strains without cross-reactivity to other Neisseria species. This sequence can also be utilized as a ligand for the sandwich capture of N. gonorrhoeae sequences and as primers for in vitro amplification. Additionally, the polypeptides encoded by this sequence, including antibodies, are disclosed along with their various uses.

Another significant patent is for a support-bound nucleotide probe for Neisseria gonorrhoeae. Similar to her previous work, this patent outlines a nucleotide sequence that can be used for rapid diagnostic assays, further enhancing the accuracy of detection methods for this pathogen.

Career Highlights

Throughout her career, Teresa has worked with notable companies such as Behringwerke Aktiengesellschaft and Syntex (U.S.A.) Inc. Her experience in these organizations has contributed to her expertise in the field of diagnostics and molecular biology.

Collaborations

One of her key collaborators is Charles Garrett Miyada, with whom she has worked closely on various projects related to her patents.

Conclusion

Teresa L Born's innovative work in the field of diagnostic assays has made a significant impact on the detection of Neisseria gonorrhoeae. Her contributions continue to advance the capabilities of molecular diagnostics, ensuring more accurate and reliable testing methods.