Teng Zhang

Title: Innovations of Teng Zhang in Genetic Engineering

Introduction

Teng Zhang is an innovative inventor hailing from Nanjing, China. He holds a notable patent that contributes significantly to the field of genetic engineering and polypeptide preparation. Zhang's work emphasizes enhancing the production and properties of therapeutic proteins, which has far-reaching implications for industrial applications.

Latest Patents

His most recent patent is titled "Fusion protein and its preparation method for intermediate polypeptide of Semaglutide." This invention reveals a novel fusion protein that includes a fusion peptide, a protease cleavage site, and a target main molecular sequence. By optimizing the fusion peptide sequence, Zhang has managed to increase the expression of the fusion protein to an impressive 13.1 g/L. The improvements also enhance the fusion protein's properties, facilitating better extraction, enzyme digestion, and purification processes. Notably, the yield of the intermediate polypeptide after enzyme digestion reaches 3.62 g/L, significantly lowering the production costs associated with Semaglutide, thereby making it suitable for industrial scale-up.

Career Highlights

Teng Zhang is currently working at Nanjing Hanxin Pharmaceutical Technology Co., Ltd., where he applies his expertise in genetic engineering to advance pharmaceutical technologies. His contributions are vital to the development of economically viable methods for producing complex therapeutic molecules.

Collaborations

Throughout his career, Zhang has collaborated with notable professionals, including Jing Wang, to explore further advancements in the pharmaceutical sector. These partnerships have helped in maximizing the impact and reach of his innovative ideas while fostering a collective approach to problem-solving in genetic engineering.

Conclusion

Teng Zhang's inventive work represents a significant leap in the field of genetic engineering, making therapeutic proteins more accessible for industrial production. His commitment to innovation continues to pave the way for advancements in biotechnology, which are crucial for developing effective treatments and improving healthcare globally.