Company Filing History:
Years Active: 1998-2002
Title: Talia Spanier: Innovator in Thrombosis Inhibition
Introduction
Talia Spanier is a prominent inventor based in New York, NY (US). She has made significant contributions to the field of medicine, particularly in the area of thrombosis inhibition. With a total of 2 patents, her work is paving the way for advancements in patient care during critical medical procedures.
Latest Patents
One of Spanier's latest patents is a method for inhibiting thrombosis in a patient whose blood is subjected to extracorporeal circulation. This invention provides a method that involves contacting the extracorporeal circulating blood with a Factor IXa compound in an effective amount to inhibit thrombosis. The Factor IXa compound may include an active site-blocked Factor IXa compound or Glu-Gly-Arg chloromethyl ketone-inactivated human factor IXa compound. The effective amount may range from about 0.1 µg/ml plasma to about 250 µg/ml plasma. This method is particularly useful during transplant surgery or cardiopulmonary bypass surgery.
Another significant patent by Spanier is an assay to monitor the antithrombic activity of a Factor IXa compound infused into a patient's circulation. This assay includes several steps, such as obtaining Factor IXa-deficient plasma and measuring the time necessary for clot formation in the incubate. This innovative approach allows for effective monitoring of antithrombic activity, enhancing patient safety during medical procedures.
Career Highlights
Talia Spanier is affiliated with Columbia University, where she continues her research and development in thrombosis inhibition. Her work is recognized for its potential to improve outcomes for patients undergoing complex medical treatments.
Collaborations
Spanier collaborates with esteemed colleagues, including Eric A. Rose and David M. Stern. These partnerships enhance her research efforts and contribute to the advancement of medical science.
Conclusion
Talia Spanier is a trailblazer in the field of thrombosis inhibition, with her innovative patents and research efforts making a significant impact on patient care. Her contributions are vital in the ongoing quest for safer medical procedures.