Sakai, Japan

Takayasu Sonoyama


Average Co-Inventor Count = 3.8

ph-index = 5

Forward Citations = 171(Granted Patents)


Location History:

  • Sakai, JA (1976)
  • Osaka, JP (1985 - 1993)
  • Sakai, JP (1981 - 1995)

Company Filing History:


Years Active: 1976-1995

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11 patents (USPTO):Explore Patents

Title: Takayasu Sonoyama: Innovator in Biochemical Engineering

Introduction

Takayasu Sonoyama is a prominent inventor based in Sakai, Japan. He has made significant contributions to the field of biochemical engineering, particularly in the development of methods for producing optically active compounds and enzymes. With a total of 11 patents to his name, Sonoyama's work has had a substantial impact on the pharmaceutical industry.

Latest Patents

Sonoyama's latest patents include a method for producing optically active norborneol through ester hydrolysis. He has also developed a cephalosporin acetylhydrolase gene and the protein encoded by this gene. This invention involves a recombinant DNA molecule prepared by introducing the gene into a vector used in an E. coli host-vector system. The E. coli cells transformed with this recombinant DNA molecule produce a protein that has the amino acid sequence encoded by the gene. Additionally, the enzyme, which is a multimer of this protein, plays a crucial role in converting cephalosporins such as cephalosporin C and 7-ACA into their deacetylated forms. These deacetylated compounds are valuable intermediates for preparing various derivatized cephalosporin antibiotics.

Career Highlights

Throughout his career, Takayasu Sonoyama has worked with notable companies, including Shionogi & Company Limited and Shionogi Seiyaku Kabushiki Kaisha. His expertise in biochemical engineering has allowed him to contribute to innovative projects that advance pharmaceutical research and development.

Collaborations

Sonoyama has collaborated with esteemed colleagues in his field, including Bunji Kageyama and Shigeo Yagi. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and the advancement of scientific knowledge.

Conclusion

Takayasu Sonoyama's contributions to biochemical engineering and his innovative patents have significantly influenced the pharmaceutical industry. His work continues to pave the way for advancements in antibiotic development and production methods.

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