Company Filing History:
Years Active: 2007-2011
Title: Takaharu Maruyama: Innovator in G Protein-Coupled Receptor Research
Introduction
Takaharu Maruyama is a notable inventor based in Ibaraki, Japan. He has made significant contributions to the field of biochemistry, particularly in the study of G protein-coupled receptors (GPCRs). With a total of 3 patents, his work has implications for pharmaceutical development and signal transduction research.
Latest Patents
Maruyama's latest patents include groundbreaking research on the guanosine triphosphate (GTP)-binding protein-coupled receptor protein known as BG37. The inventors conducted a similarity search of the amino acid sequence of known GPCR proteins in GenBank, leading to the identification of a novel human GPCR gene, BG37. The cDNA containing the open reading frame (ORF) of this gene was cloned, and its nucleotide sequence was determined. Additionally, novel GPCR BG37 genes from mouse and rat were isolated. The use of this novel GPCR enables the screening of ligands, compounds that inhibit ligand binding, and candidate pharmaceutical compounds that can regulate signal transduction from the BG37 receptor.
Career Highlights
Throughout his career, Maruyama has worked with prominent companies in the pharmaceutical industry, including Banyu Pharmaceutical Co. Ltd and Merck Sharp & Dohme Corporation. His research has been pivotal in advancing the understanding of GPCRs and their role in various biological processes.
Collaborations
Some of Maruyama's notable coworkers include Takao Nakamura and Ken-ichi Tanaka. Their collaborative efforts have contributed to the success of his research and the development of innovative solutions in the field.
Conclusion
Takaharu Maruyama's contributions to the field of G protein-coupled receptor research highlight his role as an influential inventor. His patents and collaborations continue to impact pharmaceutical research and development.