Company Filing History:
Years Active: 2003
Title: Innovations in Gene Silencing: The Contributions of Susan Mary Angell
Introduction
Susan Mary Angell is a notable inventor based in Norwich, GB. He has made significant contributions to the field of plant biotechnology, particularly in the area of gene silencing. His work has implications for agricultural practices and the development of transgenic plants.
Latest Patents
Angell holds a patent for "Methods and DNA constructs for gene silencing in transgenic plants." This invention presents DNA constructs that include a promoter linked to DNA, which can be transcribed in a plant cell to produce an RNA transcript. The RNA transcript contains plant virus sequences from an RNA virus, enabling it to replicate in the cytoplasm of the plant cell. Importantly, the transcript lacks parts of the viral genome that are not necessary for replication. Additionally, it includes at least one targeting sequence that is foreign to the plant virus sequence, facilitating post-transcriptional gene silencing of one or more target genes. The patent also outlines methods for utilizing this DNA construct to achieve gene silencing in plants.
Career Highlights
Angell's career is marked by his innovative research and development in the field of plant biotechnology. His work has contributed to advancements in genetic engineering and the potential for improved crop resilience and productivity.
Collaborations
Angell has collaborated with David Charles Baulcombe, a fellow researcher in the field. Their partnership has likely enhanced the scope and impact of their research endeavors.
Conclusion
Susan Mary Angell's contributions to gene silencing in transgenic plants represent a significant advancement in agricultural biotechnology. His innovative approaches have the potential to transform how we understand and manipulate plant genetics for better crop outcomes.