Susan A Martinis

Title: Innovations by Susan A Martinis

Introduction

Susan A Martinis is a prominent inventor based in Houston, TX (US). She has made significant contributions to the field of biochemistry, particularly in the area of tRNA synthetases. Her work focuses on developing methods and compositions that enhance the functionality of aminoacylation processes.

Latest Patents

Susan A Martinis holds a patent for a method and composition for leucyl-tRNA synthetases and derivatives thereof. This invention allows for the activation and aminoacylation of non-leucine amino acids to tRNA adaptor molecules. The patent describes a method that can generate custom-designed protein products for various applications, including medicinal, therapeutic, diagnostic, biotechnology, engineering, and spectroscopy uses. The invention addresses the natural misactivation and misaminoacylation of noncognate amino acids by tRNA synthetases, which have evolved proofreading mechanisms to correct these errors. By inactivating the enzyme's editing activity, the production of misaminoacylated tRNAs is facilitated, allowing for the introduction of novel amino acids into proteins.

Career Highlights

Susan A Martinis is affiliated with the University of Houston System, where she continues her research and development in biochemistry. Her innovative work has positioned her as a key figure in her field, contributing to advancements in protein engineering and biotechnology.

Collaborations

Some of her notable coworkers include James M Briggs and Richard S Mursinna, who have collaborated with her on various research projects.

Conclusion

Susan A Martinis is an influential inventor whose work in tRNA synthetases has the potential to revolutionize protein engineering. Her contributions to the field are significant and continue to inspire future innovations.