Su S Wang

Title: The Innovations of Su S Wang

Introduction

Su S Wang is a notable inventor based in Belmont, California, recognized for her contributions to the field of peptide synthesis and diagnostics. With a total of four patents to her name, she has made significant advancements in the methodologies used for synthesizing important biological compounds.

Latest Patents

One of her latest patents focuses on a solid-phase process for synthesizing thymosin .alpha..sub.1. This innovative method utilizes 4-methyloxybenzyloxycarbonyl (Moz) to protect the alpha amino groups of the amino acids involved in the synthesis. The Moz group can be efficiently removed using 5-10% trifluoroacetic acid in CH.sub.2 Cl.sub.2, leading to higher yields and purities compared to traditional Boc-amino acids. Additionally, the use of tributylamine as a neutralization agent enhances the recovery and recycling of solvents, allowing for the distillation of methylene chloride without contamination. The preferred resin support for this process is methylbenzhydrylamine resin. Cleavage from the resin and deprotection of thymosin .alpha..sub.1 can be achieved using HBr or trifluoromethane sulfonic acid in trifluoroacetic acid, with scavengers such as anisole and thioanisole.

Another significant patent involves a diagnostic method and test kit for the serological detection of AIDS. This invention includes a peptide of up to 40 amino acids that encompasses the core sequence of the p17 gag core protein of HIV-1, specifically targeting amino acids at positions 92-109.

Career Highlights

Throughout her career, Su S Wang has worked with prominent companies such as Alpha 1 Biomedicals and Viral Technologies, Inc. Her work has contributed to advancements in biomedical research and therapeutic applications.

Collaborations

Su S Wang has collaborated with various professionals in her field, including her coworker Allan L Goldstein, enhancing the impact of her research and innovations.

Conclusion

Su S Wang's contributions to peptide synthesis and diagnostics have paved the way for significant advancements in biomedical research. Her innovative approaches continue to influence the field and improve methodologies for synthesizing vital biological compounds.