Steven M Rodems

Title: The Innovations of Steven M. Rodems

Introduction

Steven M. Rodems is an accomplished inventor based in Poway, California. He is known for his significant contributions to the field of optical probes and assays. His work has implications in various scientific and medical applications, particularly in understanding post-translational modifications.

Latest Patents

Rodems holds a patent for his invention titled "Optical probes and assays." This invention provides an optical probe that serves as a sensor for post-translational type modifications, such as phosphorylation. The optical probe comprises a polypeptide moiety with a recognition motif for post-translational activity and a protease site coupled to a probe moiety. The modification of the polypeptide by the post-translational activity modulates the rate at which a protease cleaves the polypeptide. This modulation is sensed by a measurable change in at least one optical property of the probe upon cleavage. Additionally, the invention includes a recombinant nucleic acid molecule encoding the optical probe, along with a vector and host cell or library of cells that contain the recombinant nucleic acid molecule. The optical probe can be utilized in methods to determine whether a sample contains a post-translational modification activity, and it can also identify therapeutic compositions.

Career Highlights

Steven M. Rodems is associated with Aurora Biosciences Corporation, where he has made significant contributions to the field of biotechnology. His work has been instrumental in advancing the understanding of optical probes and their applications in various scientific domains.

Collaborations

Rodems has collaborated with notable colleagues, including Brian Pollok and Brian D. Hamman. These collaborations have further enhanced the development and application of his inventions.

Conclusion

Steven M. Rodems is a prominent inventor whose work in optical probes has the potential to revolutionize the detection of post-translational modifications. His contributions to Aurora Biosciences Corporation and collaborations with esteemed colleagues underscore his impact in the field.