Company Filing History:
Years Active: 2007
Title: Innovations of Steven Burmaster in Stabilizing 5-Azacytidine
Introduction
Steven Burmaster is an accomplished inventor based in Lee's Summit, MO (US). He has made significant contributions to the field of pharmaceuticals, particularly in the stabilization of 5-azacytidine. His innovative methods have the potential to enhance the storage and determination of this important compound.
Latest Patents
Steven Burmaster holds a patent for "Methods for stabilizing 5-azacytidine in plasma." This invention provides methods for stabilizing 5-azacytidine against hydrolysis in plasma. By extracting the 5-azacytidine into acetonitrile and zinc sulfate, the compound can be stored for at least about 3 hours at room temperature and for at least about 4 days at -70°C. If the acetonitrile is removed and evaporated to dryness, the 5-azacytidine in the resulting residue remains stable for at least about 14 months at -70°C. The invention also includes methods for determining the 5-azacytidine in acetonitrile or in the acetonitrile residue, utilizing techniques such as high-performance liquid chromatography.
Career Highlights
Steven Burmaster is associated with Pharmion Corporation, where he has been able to apply his expertise in pharmaceutical innovations. His work has contributed to advancements in the stability and analysis of critical compounds used in medical treatments.
Collaborations
Throughout his career, Steven has collaborated with notable colleagues, including Marsha Luna and Larry Eden. These partnerships have fostered a collaborative environment that encourages innovation and the development of new methodologies.
Conclusion
Steven Burmaster's contributions to the stabilization of 5-azacytidine represent a significant advancement in pharmaceutical science. His innovative methods not only enhance the storage capabilities of this compound but also improve the accuracy of its determination in laboratory settings.