Company Filing History:
Years Active: 2018-2025
Title: Innovations by Inventor Stephan M Koza
Introduction
Stephan M Koza is a notable inventor based in Lancaster, MA (US). He has made significant contributions to the field of chromatography, particularly in the analysis of glycoproteins and glycopeptides. With a total of six patents to his name, Koza's work has advanced the methodologies used in biochemical analysis.
Latest Patents
One of Koza's latest patents focuses on materials for hydrophilic interaction chromatography (HILIC) and processes for their preparation and use. This invention relates to poly-amide bonded HILIC stationary phases and novel methods for characterizing large biological molecules modified with polar groups, known as glycans. The invention provides innovative materials designed for efficient separation of large biomolecules, featuring a high percentage of larger pores. Additionally, it addresses challenges such as on-column aggregation of protein samples and low sensitivity in chromatographic detection of glycan moieties. Another significant patent involves methods for the rapid preparation of labeled glycosylamines and the analysis of glycosylated biomolecules. This method allows for the production of derivatized glycosylamines with high yields and minimal overlabeling, utilizing advanced detection techniques.
Career Highlights
Stephan M Koza is currently employed at Waters Technologies Corporation, a company renowned for its contributions to analytical instruments and software. His work at Waters has positioned him as a key player in the development of innovative solutions for biochemical analysis.
Collaborations
Koza has collaborated with several professionals in his field, including Matthew A Lauber and Pamela Carmen Iraneta. These collaborations have further enhanced the impact of his inventions and contributed to advancements in chromatography.
Conclusion
Stephan M Koza's contributions to the field of chromatography through his innovative patents have significantly advanced the analysis of glycoproteins and glycopeptides. His work continues to influence the methodologies used in biochemical research and analysis.