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Years Active: 2022
Title: Soline Estrach: Innovator in Skin Affliction Treatments
Introduction
Soline Estrach is a notable inventor based in Nice, France. She has made significant contributions to the field of dermatology through her innovative research and development of methods for treating skin afflictions. Her work focuses on utilizing small extracellular vesicles (sEVs) to improve skin health and healing.
Latest Patents
Soline Estrach holds a patent for "Methods and compositions for treating skin afflictions." This invention relates to a method for treating skin afflictions in a subject by administering a therapeutically effective amount of small extracellular vesicles (sEV) comprising CD98hc. The research demonstrates that healthy dermal fibroblasts produce and secrete EVs that exhibit characteristics of exosome-like small EVs. The presence of CD98hc on the surface of these sEVs has been shown to transfer and stabilize at the plasma membrane of recipient cells. The findings indicate that the transferred protein is functional both in vitro and in vivo. Notably, the injection of sEVs in epidermal CD98hc knockout mice, which exhibit wound healing defects, has been shown to rescue wound closure in vivo. This research reveals the potential of CD98hc contained in EVs to treat and improve multiple skin afflictions by facilitating protein rescue.
Career Highlights
Throughout her career, Soline Estrach has worked with esteemed institutions, including the National Institute of Health and Medical Research (Institut National De La Sante Et De La Recherche Medicale) and the University of Nice Sophia Antipolis. Her dedication to advancing medical science has positioned her as a key figure in her field.
Collaborations
Soline has collaborated with talented individuals such as Chloé Feral and Floriane Tissot. Their combined efforts have contributed to the success of her research and innovations.
Conclusion
Soline Estrach's work in developing methods for treating skin afflictions showcases her innovative spirit and commitment to improving healthcare. Her contributions to the field of dermatology through her patent and collaborations highlight the importance of research in advancing medical treatments.