Company Filing History:
4 out of 4,455 
4 out of 78 Years Active: 2009-2016
Title: Innovations and Contributions of Shelley Sims Belouski
Introduction
Shelley Sims Belouski is a notable inventor based in Camarillo, California. She has made significant contributions to the field of biotechnology, particularly in the development of antibodies for therapeutic applications. With a total of four patents to her name, her work has had a substantial impact on medical research and treatment methodologies.
Latest Patents
One of her latest patents involves nucleic acids encoding antibodies to CCR2. This invention provides antibodies, including human antibodies and antigen-binding portions, that specifically bind to CCR2, preferably human CCR2, and may inhibit its function. The antibodies can bind to the first and/or second extracellular loops of CCR2. Additionally, the patent includes isolated heavy and light chains derived from these antibodies, as well as methods for making and using them in diagnosis and treatment. Another significant patent pertains to human monoclonal antibodies to activin receptor-like kinase-1 (ALK-1). This invention relates to antibodies that bind to the extracellular domain of ALK-1 and function to abrogate the ALK-1/TGF-beta-1/Smad1 signaling pathway. It also encompasses heavy and light chain immunoglobulins derived from these antibodies and methods for their production and application.
Career Highlights
Shelley has worked with prominent companies in the biotechnology sector, including Pfizer Corporation and Amgen Fremont Inc. Her experience in these organizations has allowed her to develop her expertise in antibody research and therapeutic applications.
Collaborations
Throughout her career, Shelley has collaborated with esteemed colleagues, including Ronald P. Gladue and Bradley T. Keller. These collaborations have contributed to her innovative work and the advancement of her research.
Conclusion
Shelley Sims Belouski's contributions to biotechnology through her patents and collaborations highlight her role as a leading inventor in the field. Her work continues to influence medical research and therapeutic strategies.