Company Filing History:
Years Active: 2017
Title: Innovations of Shauna M Paradine
Introduction
Shauna M Paradine is an accomplished inventor based in Cambridge, MA (US). She has made significant contributions to the field of chemistry, particularly in the development of catalysts for C-H functionalization. Her work is characterized by a focus on reactivity and selectivity, which has implications for various applications in organic synthesis.
Latest Patents
Shauna holds a patent for a novel general catalyst for C-H functionalization. This invention provides innovative manganese catalysts, such as [Mn(BuPc)], which are effective for the amination of various types of C(sp)-H bonds. These include aliphatic, allylic, propargylic, benzylic, and ethereal bonds, even those that are typically strong, such as 1aliphatic C—H bonds. The catalyst achieves excellent chemoselectivity, stereospecificity, and high functional group tolerance. Her research demonstrates the late-stage diversification of bioactive complex molecules, showcasing selective 1C—H aminations of compounds like betulinic acid and pleuromutilin derivatives. The unique balance of reactivity and selectivity in her catalysts is attributed to a mechanism of C—H amination that lies between stepwise and concerted processes.
Career Highlights
Shauna is affiliated with the University of Illinois, where she continues her research and development in the field of chemistry. Her innovative work has garnered attention and respect within the scientific community, contributing to advancements in organic synthesis and catalysis.
Collaborations
Shauna has collaborated with notable colleagues, including M Christina White and Jennifer R Griffin. These partnerships have further enhanced her research and the impact of her inventions.
Conclusion
Shauna M Paradine is a pioneering inventor whose work in catalyst development has the potential to transform organic synthesis. Her contributions to the field are marked by innovation and collaboration, making her a significant figure in contemporary chemistry.