Company Filing History:
Years Active: 2025
Title: Innovations by Shannon E Boye in Gene Therapy
Introduction
Shannon E Boye is a prominent inventor based in Gainesville, FL (US). She has made significant contributions to the field of gene therapy, particularly in the treatment of Usher syndrome IB (USH1B). Her innovative work focuses on developing advanced vector systems for delivering therapeutic genes to the eye and inner ear.
Latest Patents
Shannon E Boye holds a patent for "Dual AAV-MYO7A vectors with improved safety for the treatment of USH1B." This patent discloses compositions and methods aimed at treating diseases of the mammalian eye, specifically complications of the retina associated with Usher syndrome IB. Additionally, it addresses complications of ear hair cells related to the same syndrome. The invention provides improved AAV-based, dual vector systems that enable the expression of full-length proteins, overcoming the limitations of individual AAV vector packaging capacity. The patent describes modified hybrid dual vector systems that strategically shift the coding sequence for the MY07A tail domain to prevent the production of truncated MY07A protein. Furthermore, it includes improved codon-modified hybrid and overlap vector systems that eliminate putative stop codons and residual sequences in non-coding regions.
Career Highlights
Shannon E Boye is affiliated with the University of Florida Research Foundation, Incorporated. Her work has been instrumental in advancing gene therapy techniques, particularly for genetic disorders affecting vision and hearing. She has dedicated her career to researching and developing innovative solutions that improve patient outcomes.
Collaborations
Shannon collaborates with notable colleagues, including Sanford L Boye and H Lee Sweeney. Their combined expertise enhances the research and development of gene therapy applications.
Conclusion
Shannon E Boye's contributions to gene therapy, particularly through her patent on dual AAV-MYO7A vectors, represent a significant advancement in the treatment of Usher syndrome IB. Her work continues to inspire innovation in the field of genetic medicine.