Shane M Lamos

Title: Innovations in Mass Spectrometry by Shane M Lamos

Introduction

Shane M Lamos is a notable inventor based in Winooski, Vermont, who has made significant contributions to the field of mass spectrometry. With a focus on ionizable isotopic labeling reagents, her work has advanced the relative quantification of metabolites, enhancing the accuracy and sensitivity of mass spectrometric analyses.

Latest Patents

Shane Lamos holds 2 patents, with her latest innovations centered around the development of ionizable isotopic labeling reagents for relative quantification by mass spectrometry. These reagents facilitate the simultaneous analysis of multiple analytes in two or more samples. By synthesizing heavy and light isotopic forms of methylacetimidate, formaldehyde, and cholamine, she has created labeling reagents that are reactive to specific compound classes. This innovation allows for the quantification of amine-containing and carboxylic acid-containing molecules found in biological samples. The labeled end-products exhibit positive charges under normal acidic conditions, which significantly improves the sensitivity and accuracy of conventional Liquid Chromatography Mass Spectrometry (LC/MS) applications.

Career Highlights

Throughout her career, Shane has worked with esteemed organizations such as the Wisconsin Alumni Research Foundation and the University of Illinois. Her research has led to improved methodologies for quantifying metabolites, showcasing her expertise in the field of mass spectrometry.

Collaborations

Shane has collaborated with notable colleagues, including Lloyd M Smith and Michael Robert Shortreed, further enhancing the impact of her research through teamwork and shared expertise.

Conclusion

Shane M Lamos is a pioneering inventor whose work in mass spectrometry has significantly advanced the field. Her innovative approaches to isotopic labeling have improved the accuracy and sensitivity of metabolite quantification, making her a valuable contributor to scientific research.