Shalley K Gupta

Title: Shalley K Gupta: Innovator in Platelet Factor Research

Introduction

Shalley K Gupta is a notable inventor based in Indianapolis, IN (US). She has made significant contributions to the field of biomedical research, particularly in the study of modified forms of human platelet factor-4. With a total of 3 patents to her name, Gupta's work has the potential to impact the treatment of various angiogenic diseases.

Latest Patents

Gupta's latest patents focus on the discovery of two modified forms of human platelet factor-4, referred to as MPF-4 and CPF-4. These forms were isolated from serum-free culture medium of lipopolysaccharide-stimulated peripheral blood leukocytes. The amino acid sequence determination revealed that MPF-4 shares homology with platelet factor-4 beginning at N-terminal residue 17. CPF-4 consists of MPF-4 disulfide bonded to the 16 N-terminal residues of platelet factor-4. Both MPF-4 and CPF-4 are identified as potent inhibitors of endothelial cell proliferation, being approximately 10-100 fold more effective than native or recombinant platelet factor-4. This makes them valuable in the treatment of angiogenic diseases.

Career Highlights

Shalley K Gupta is currently employed at Eli Lilly and Company, where she continues her research and development efforts. Her work at this prominent pharmaceutical company allows her to collaborate with other experts in the field and contribute to innovative solutions in healthcare.

Collaborations

One of Gupta's notable coworkers is Jai P Singh, who plays a significant role in her research endeavors. Their collaboration enhances the potential for groundbreaking discoveries in the field of platelet factor research.

Conclusion

Shalley K Gupta's innovative work in the field of modified platelet factor-4 showcases her dedication to advancing medical science. Her contributions have the potential to lead to significant advancements in the treatment of angiogenic diseases.