Company Filing History:
Years Active: 1998-2001
Title: The Innovations of Serguei V Kotenko
Introduction
Serguei V Kotenko is a notable inventor based in Highland Park, NJ (US). He has made significant contributions to the field of medicine and biotechnology, holding 2 patents that reflect his innovative spirit and dedication to advancing scientific knowledge.
Latest Patents
Kotenko's latest patents include groundbreaking work on the accessory factory function for interferon gamma and its receptor. This invention encompasses several key components: the development of a 540 kb YAC that encodes necessary species-specific factors to substitute for human Chromosome 21, the construction of a plasmid for integrating selective markers for antibiotic G418 resistance into YACs, and the creation of fragmentation vectors for targeting YACs containing human genomic DNA. Additionally, his work involves a chromosomal fragmentation procedure to produce a deletion set of YACs and the isolation of cDNA clones that can reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens. Another significant patent relates to the identification of intracellular signal transduction functions for the IL-10 receptor, which includes preparing recombinant cells that express the IL-10 receptor and the newly identified IL-10 signal transduction protein.
Career Highlights
Kotenko's career is marked by his association with the University of Medicine and Dentistry of New Jersey, where he has contributed to various research initiatives. His work has been pivotal in understanding the mechanisms of cytokine receptors and their roles in immune responses.
Collaborations
Throughout his career, Kotenko has collaborated with esteemed colleagues such as Sidney Pestka and Jaemog Soh. These partnerships have enhanced the scope and impact of his research, leading to advancements in the field.
Conclusion
Serguei V Kotenko's innovative contributions to biotechnology and medicine demonstrate his commitment to scientific advancement. His patents reflect a deep understanding of complex biological systems and have the potential to influence future research and therapeutic strategies.